Mixing Fentanyl (fent) and Tianeptine (gas station heroin)
Dangerous
Fentanyl sets the risk, and tianeptine stacks a second full opioid on top.
Do this
Do not combine. Keep naloxone nearby, and never use alone.
Where the risk isTap for why
What to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means
High risk of death or life-changing injury. Do not combine.
How the ratings workThe longer explanation
Fentanyl sets the risk, and tianeptine stacks a second full opioid on top. A tolerance built on gas-station tianeptine says nothing about fentanyl, and fentanyl is increasingly what street opioids actually are.
Sources (5)
- FDA warns consumers not to purchase or use any tianeptine product due to serious risks. 2025fda.gov
- Gassaway MM et al. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl Psychiatry. 2014nature.com
- El Zahran T et al. Characteristics of Tianeptine Exposures Reported to the National Poison Data System — United States, 2000–2017. MMWR. 2018pmc.ncbi.nlm.nih.gov
- Presence of kratom in opioid overdose deaths (fentanyl co-detection rising 33% to 62%, 2018-2022)ncbi.nlm.nih.gov
- Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanylpmc.ncbi.nlm.nih.gov
Think this is wrong, or know a better source? Send it.
Other names
- Fentanyl
- fent, fentanil, carfentanil, nitazene, nitazenes, duragesic
- Synthetic — potent by micrograms, unevenly mixed
- Tianeptine
- gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
- Sold as a supplement — at the doses people take, a full opioid
Also searched asfent and gas station heroin, carfentanil and gas station heroin, fent and tianaa, carfentanil and tianaa
Related combinations
Fentanyl withWhat not to mix with Fentanyl →
Tianeptine withWhat not to mix with Tianeptine →
All combinations →Can you mix Fentanyl (fent) and Tianeptine (gas station heroin)?
MixSafe rates mixing Fentanyl and Tianeptine as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: MixSafe research. Educational information, not medical advice.