Mixing MAOIs and Tianeptine (gas station heroin)

Dangerous

Tianeptine's label rules out MAOIs: collapse, sudden high blood pressure, overheating, convulsions and death.

Do this

Do not combine, and leave two weeks after stopping an MAOI.

Where the risk isTap for why
In an emergency, call 911911Never Use AlonePoison Control
What to do
  • Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
  • Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
  • Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
  • Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
  • Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
  • Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means

High risk of death or life-changing injury. Do not combine.

How the ratings work
The longer explanation

Tianeptine's own prescribing information rules out irreversible MAOIs because of the risk of circulatory collapse, sudden high blood pressure, overheating, convulsions and death, and asks for two weeks between stopping an MAOI and starting tianeptine. That is about prescription MAOIs; nobody has studied ayahuasca or syrian rue with it, which is not the same as safe.

Sources (1)

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Other names
MAOIs
maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
Tianeptine
gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
Sold as a supplement — at the doses people take, a full opioid
Also searched asmaois and gas station heroin, maois and tianaa
Add a third substance in the checker

Related combinations

MAOIs withWhat not to mix with MAOIs →
Tianeptine withWhat not to mix with Tianeptine →
All combinations →

Can you mix MAOIs and Tianeptine (gas station heroin)?

MixSafe rates mixing MAOIs and Tianeptine as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: MixSafe research. Educational information, not medical advice.