Mixing 2C-T-x and MAOIs
Caution
MAOIs can make 2C-T-x much stronger and longer-lasting in ways that are hard to predict. Take less of each than usual, and do not use alone.
MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably, which could be dangerous given the unpredictability of the 2C-T-x series
The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.
Headspace vs physical riskCan you mix 2C-T-x and MAOIs?
MixSafe rates mixing 2C-T-x and MAOIs as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- 2C-T-x also called
- 2c-t-2, 2c-t-7, 2c-t-21
- MAOIs also called
- maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.