Combination
Mixing Codeine and Fentanyl
OpioidOpioid
- Codeine also called
- lean, purple drank, co-codamol, dihydrocodeine
- Fentanyl also called
- fent, fentanil, carfentanil, nitazene, nitazenes
Verdict
Dangerous
Additive respiratory depression, with fentanyl setting the risk. Codeine adds little effect and meaningful danger.
Risk / Physical
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Codeine and Fentanyl?
High risk of death or life-changing injury. Do not combine.
- Codeine
- Weak, but metabolised unpredictably between people
- Fentanyl
- Synthetic — potent by micrograms, unevenly mixed
- Presence of kratom in opioid overdose deaths (fentanyl co-detection rising 33% to 62%, 2018-2022). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10806006/
- Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl. https://pmc.ncbi.nlm.nih.gov/articles/PMC11437388/
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.