Mixing Codeine (lean) and Tianeptine (gas station heroin)
Dangerous
Two opioids stacked, one of unpredictable strength and one without labelling you can trust.
Do this
Do not combine. Keep naloxone nearby.
Where the risk isTap for why
What to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means
High risk of death or life-changing injury. Do not combine.
How the ratings workThe longer explanation
Two opioids stacked: one whose strength varies unpredictably between people, and one sold as a supplement without labelling you can trust.
Sources (5)
- FDA warns consumers not to purchase or use any tianeptine product due to serious risks. 2025fda.gov
- Gassaway MM et al. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl Psychiatry. 2014nature.com
- El Zahran T et al. Characteristics of Tianeptine Exposures Reported to the National Poison Data System — United States, 2000–2017. MMWR. 2018pmc.ncbi.nlm.nih.gov
- Codeine Intoxication Associated with Ultrarapid CYP2D6 Metabolism. NEJMnejm.org
- Codeine Therapy and CYP2D6 Genotype. Medical Genetics Summaries, NCBIncbi.nlm.nih.gov
Think this is wrong, or know a better source? Send it.
Other names
- Codeine
- lean, purple drank, co-codamol, dihydrocodeine
- Weak, but metabolised unpredictably between people
- Tianeptine
- gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
- Sold as a supplement — at the doses people take, a full opioid
Also searched aslean and gas station heroin, purple drank and gas station heroin, lean and tianaa, purple drank and tianaa
Related combinations
Codeine withWhat not to mix with Codeine →
Tianeptine withWhat not to mix with Tianeptine →
All combinations →Can you mix Codeine (lean) and Tianeptine (gas station heroin)?
MixSafe rates mixing Codeine and Tianeptine as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: MixSafe research. Educational information, not medical advice.