Mixing LSD (acid) and Mescaline (peyote)
Low risk, increased effect
Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.
Can you mix LSD (acid) and Mescaline (peyote)?
MixSafe rates mixing LSD and Mescaline as "Low risk, increased effect" — low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- LSD also called
- acid, lsd-25, cid, lucy, tabs, blotter
- Mescaline also called
- peyote, san pedro, san-pedro, mesc, buttons
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.