Mixing Opioids and Tianeptine (gas station heroin)
Dangerous
Tianeptine is a full opioid sold as a supplement, so this is two opioids stacked, and it wears off fast enough to invite redosing.
Do not combine. Keep naloxone nearby, and never use alone.
What to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means
High risk of death or life-changing injury. Do not combine.
How the ratings workThe longer explanation
Tianeptine is sold as a supplement, but at the doses people take it is a full agonist at the same receptor as heroin and oxycodone, so this is two opioids stacked. It wears off fast, with a half-life of about two and a half hours, so it gets redosed often, and its withdrawal looks like opioid withdrawal, which pushes people toward other opioids to manage it. Keep naloxone nearby and never use alone.
Sources (4)
- FDA warns consumers not to purchase or use any tianeptine product due to serious risks. 2025fda.gov
- Gassaway MM et al. The atypical antidepressant and neurorestorative agent tianeptine is a μ-opioid receptor agonist. Transl Psychiatry. 2014nature.com
- El Zahran T et al. Characteristics of Tianeptine Exposures Reported to the National Poison Data System — United States, 2000–2017. MMWR. 2018pmc.ncbi.nlm.nih.gov
- Stablon (tianeptine) prescribing information. Servierserviermalaysia.com
Think this is wrong, or know a better source? Send it.
Other names
- Tianeptine
- gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
- Sold as a supplement — at the doses people take, a full opioid
Related combinations
Can you mix Opioids and Tianeptine (gas station heroin)?
MixSafe rates mixing Opioids and Tianeptine as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: MixSafe research. Educational information, not medical advice.