Combination

Mixing Alcohol and Opioids

DepressantOpioid
Alcohol also called
booze, beer, wine, liquor, ethanol, etoh
Opioids also called
opiate, opiates, opioid, heroin, dope, smack
Verdict

Dangerous

Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. Place the affected individual in the recovery position to prevent vomit aspiration from excess. Memory blackouts are likely

Risk / Physical

The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.

Can you mix Alcohol and Opioids?

High risk of death or life-changing injury. Do not combine.

Opioids
Full agonists — heroin, oxycodone, morphine
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

Open this in the checker

Related combinations

All combinations →

Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.