Mixing PCP (angel dust) and Tianeptine (gas station heroin)

Caution

PCP can lower your opioid tolerance, making an overdose more likely.

Do this

Take less opioid than usual, do not use alone, and keep naloxone nearby.

General answer for Opioids: nothing specific to these two is documented.

Where the risk isTap for why
What “Caution” means

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

How the ratings work
The longer explanation

PCP can reduce opioid tolerance, increasing the risk of overdose

Sources (1)

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Other names
PCP
phencyclidine, angel dust, angeldust, wet, sherm
Tianeptine
gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
Sold as a supplement — at the doses people take, a full opioid
Also searched asangel dust and gas station heroin, phencyclidine and gas station heroin, angel dust and tianaa, phencyclidine and tianaa
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Related combinations

PCP withWhat not to mix with PCP →
Tianeptine withWhat not to mix with Tianeptine →
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Can you mix PCP (angel dust) and Tianeptine (gas station heroin)?

MixSafe rates mixing PCP and Tianeptine as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to PCP and Tianeptine is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.