Combination

Mixing Amphetamines and DOx

StimulantPsychedelic
Amphetamines also called
adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
DOx also called
dom, doc, doi, dob, don
Verdict

Unsafe

The combined stimulating effects of the two can lead to an uncomfortable body-load, while the focusing effects of amphetamine can easily lead to thought loops. Coming down from amphetamines while the DOx is still active can be quite anxiogenic.

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix Amphetamines and DOx?

Risk of serious physical or psychological harm. Not recommended under any circumstances.

Amphetamines
Prescription and street speed — Adderall, dexamphetamine
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.