Caution

The stimulant hides how much the opioid is slowing you; if it wears off first, breathing can stop.

Do this

Take less of each than usual, do not use alone, and keep naloxone nearby.

General answer for Opioids: nothing specific to these two is documented.

Where the risk isTap for why
What “Caution” means

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

How the ratings work
The longer explanation

Stimulants increase respiration rate, which can allow for a higher dose of opiates normal . If the stimulant wears off first then the opiate may overcome the individual and cause respiratory arrest.

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Other names
Amphetamines
adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
Prescription and street speed — Adderall, dexamphetamine
Tianeptine
gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
Sold as a supplement — at the doses people take, a full opioid
Also searched asAdderall and gas station heroin, speed and gas station heroin, Adderall and tianaa, speed and tianaa

Related combinations

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Can you mix Amphetamines (Adderall) and Tianeptine (gas station heroin)?

MixSafe rates mixing Amphetamines and Tianeptine as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to Amphetamines and Tianeptine is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.