Dangerous

High risk of death or life-changing injury. Do not combine.

Do this

Do not combine. If you already have, do not take more, stay with someone, and call emergency services if they cannot be woken.

General answer for Amphetamines: nothing specific to these two is documented.

Where the risk isTap for why
In an emergency, call 911911Never Use AlonePoison Control
What to do
  • Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
  • Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
  • Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
  • Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
  • Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means

High risk of death or life-changing injury. Do not combine.

How the ratings work
Sources (1)

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Other names
AMT
alpha-methyltryptamine, alphamethyltryptamine, indopan, monase
Methylphenidate
ritalin, ritalin la, concerta, focalin, dexmethylphenidate, methylin
Not an amphetamine, but mixes much like one — most answers here are Adderall's
Also searched asamt and Ritalin, amt and ritalin la

Related combinations

All combinations →

Can you mix AMT and Methylphenidate (Ritalin)?

MixSafe rates mixing AMT and Methylphenidate as "Dangerous" — high risk of death or life-changing injury. Do not combine. No interaction specific to AMT and Methylphenidate is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.