Mixing Cannabis (weed) and Opioids
Low risk, increased effect
Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.
Can you mix Cannabis (weed) and Opioids?
MixSafe rates mixing Cannabis and Opioids as "Low risk, increased effect" — low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- Opioids
- Full agonists — heroin, oxycodone, morphine
- Cannabis also called
- weed, pot, marijuana, thc, hash, edibles
- Opioids also called
- opiate, opiates, opioid, heroin, dope, smack
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.