Unsafe

The stimulant hides how sedated you are, and the fentanyl is still working when it wears off.

Do this

Avoid this combination; test pills sold as Adderall, never use alone, and keep naloxone nearby.

General answer for Amphetamines: nothing specific to these two is documented.

Where the risk isTap for why
In an emergency, call 911911Never Use AlonePoison Control
What to do
  • Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
  • Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
  • Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
  • Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
  • Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
  • Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Unsafe” means

Risk of serious physical or psychological harm. Not recommended under any circumstances.

How the ratings work
The longer explanation

Same mechanism as fentanyl with meth or cocaine: the stimulant hides how sedated you are, so fentanyl gets redosed, and it is still working when the stimulant wears off. Pressed pills sold as Adderall are a known route for fentanyl, so test them too.

Sources (2)
Other names
Fentanyl
fent, fentanil, carfentanil, nitazene, nitazenes, duragesic
Synthetic — potent by micrograms, unevenly mixed
Methylphenidate
ritalin, ritalin la, concerta, focalin, dexmethylphenidate, methylin
Not an amphetamine, but mixes much like one — most answers here are Adderall's
Also searched asfent and Ritalin, carfentanil and Ritalin, fent and ritalin la, carfentanil and ritalin la

Related combinations

All combinations →

Can you mix Fentanyl (fent) and Methylphenidate (Ritalin)?

MixSafe rates mixing Fentanyl and Methylphenidate as "Unsafe" — risk of serious physical or psychological harm. Not recommended under any circumstances. No interaction specific to Fentanyl and Methylphenidate is documented; this is the default for Amphetamines. Source: MixSafe research. Educational information, not medical advice.

This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.