Dangerous
Each makes the other much stronger, fast and unpredictably, so people pass out quickly.
Do not combine. Keep naloxone nearby, and put anyone who passes out on their side.
General answer for Opioids: nothing specific to these two is documented.
What to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means
High risk of death or life-changing injury. Do not combine.
How the ratings workThe longer explanation
The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position
Sources (1)
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Other names
- GHB / GBL
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
- Tianeptine
- gas station heroin, tianaa, zaza red, neptune's fix, pegasus, td red
- Sold as a supplement — at the doses people take, a full opioid
Related combinations
Can you mix GHB / GBL (liquid G) and Tianeptine (gas station heroin)?
MixSafe rates mixing GHB / GBL and Tianeptine as "Dangerous" — high risk of death or life-changing injury. Do not combine. No interaction specific to GHB / GBL and Tianeptine is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.