Mixing GHB / GBL and MXE
Dangerous
Both wreck coordination and can cause vomiting and unconsciousness. Do not combine. If someone passes out, put them on their side so they cannot choke on vomit.
Both substances cause ataxia and bring a risk of vomiting and unconsciousness. If the individual falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.
This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.
Headspace vs physical riskWhat to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
Can you mix GHB / GBL and MXE?
MixSafe rates mixing GHB / GBL and MXE as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- GHB / GBL also called
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
- MXE also called
- methoxetamine
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Open this in the checkerRelated combinations
All combinations →Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.