Mixing LSD (acid) and Mephedrone (meow)
Caution
The stimulant makes a trip more anxious and loop-prone, and together they can overwork the heart. Take less of each than usual, and do not use alone.
The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops, in addition to the possible negative side effects of coming down from said stimulant while on a psychedelic. In extreme cases, stimulants, especially in combination can result in severe vasoconstriction, tachycardia, hypertension, and heart failure.
The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.
Headspace vs physical riskCan you mix LSD (acid) and Mephedrone (meow)?
MixSafe rates mixing LSD and Mephedrone as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- LSD also called
- acid, lsd-25, cid, lucy, tabs, blotter
- Mephedrone also called
- 4-mmc, 4mmc, meow, m-cat, 4-methylmethcathinone, bath salts
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
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All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.