Mixing Methamphetamine (meth) and NBOMes
Unsafe
Together they overwork the heart and raise the risk of a seizure, and the trip is more loop-prone. Avoid this combination.
Amphetamines and NBOMes both provide considerable stimulation. When combined they can result in tachycardia, hypertension, vasoconstriction and in extreme cases heart failure. The anxiogenic and focusing effects of stimulants are also not good in combination with psychedelics as they can lead to unpleasant thought loops. NBOMes are known to cause seizures and stimulants can increase this risk.
This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.
Headspace vs physical riskWhat to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
Can you mix Methamphetamine (meth) and NBOMes?
MixSafe rates mixing Methamphetamine and NBOMes as "Unsafe" — risk of serious physical or psychological harm. Not recommended under any circumstances. No interaction specific to Methamphetamine and NBOMes is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
- NBOMes also called
- 25i, 25i-nbome, 25c-nbome, 25b-nbome, n-bomb, nbome
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
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All combinations →Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.