Combination

Mixing Alcohol and Mushrooms

DepressantPsychedelic
Alcohol also called
booze, beer, wine, liquor, ethanol, etoh
Mushrooms also called
shrooms, psilocybin, psilocybin mushrooms, mushroom, psylocybin, caps
Verdict

Low risk, decreased effect

Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.

Can you mix Alcohol and Mushrooms?

Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated low / decrease. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.