Mixing Amphetamines (Adderall) and Lithium
Low risk, no synergy
Lithium may be neuroprotective when taken with amphetamines and lithium may decrease the hyperactive and euphoric effects of amphetamines. Lithium may also decrease some negative side effects of amphetamines. Studies indicate this combination is safe.
Can you mix Amphetamines (Adderall) and Lithium?
MixSafe rates mixing Amphetamines and Lithium as "Low risk, no synergy" — neither substance is expected to meaningfully change the other. Both still carry their own individual risks. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- Amphetamines
- Prescription and street speed — Adderall, dexamphetamine
- Amphetamines also called
- adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
- Lithium also called
- lithium carbonate, lithobid, mood stabilizer
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.