Combination
Mixing Benzodiazepines and Lithium
DepressantOther
- Benzodiazepines also called
- benzodiazepine, benzos, benzo, xanax, alprazolam, valium
- Lithium also called
- lithium carbonate, lithobid, mood stabilizer
Verdict
Low risk, no synergy
Commonly co-prescribed and not known to interact directly. Expect additive sedation only.
Can you mix Benzodiazepines and Lithium?
Neither substance is expected to meaningfully change the other. Both still carry their own individual risks.
- Nayak SM et al., Johns Hopkins, 2021. https://pure.johnshopkins.edu/en/publications/classic-psychedelic-coadministration-with-lithium-but-not-lamotri/
- Ibuprofen interactions to avoid (renal lithium clearance). https://www.singlecare.com/blog/ibuprofen-interactions/
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Benzodiazepines withWhat not to mix with Benzodiazepines →
Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.