Mixing Benzodiazepines and Tramadol
- Benzodiazepines also called
- benzodiazepine, benzos, benzo, xanax, alprazolam, valium
- Tramadol also called
- tram, ultram
Dangerous
Central nervous system- and/or respiratory-depressant effects may be additively or synergistically present. Vomit aspiration is a risk when passed out, lay down in recovery position if ingested.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Benzodiazepines and Tramadol?
High risk of death or life-changing injury. Do not combine.
- Tramadol
- Opioid plus serotonin reuptake inhibition, and seizure risk
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.