Mixing Cocaine (coke) and GHB / GBL
Caution
Each hides the other; whichever wears off first leaves you with a dangerous amount of the other. Take less of each than usual, and do not use alone.
Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opiate may overcome the individual and cause respiratory arrest. Likewise the ghb/gbl can wear off and leave a dangerous concentration of cocaine behind
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Headspace vs physical riskCan you mix Cocaine (coke) and GHB / GBL?
MixSafe rates mixing Cocaine and GHB / GBL as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- Cocaine also called
- coke, crack, blow, snow, yayo, yay
- GHB / GBL also called
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.