Combination

Mixing Codeine (lean) and DOx

OpioidPsychedelic
Verdict

Low risk, no synergy

No unexpected interactions.

Can you mix Codeine (lean) and DOx?

MixSafe rates mixing Codeine and DOx as "Low risk, no synergy" — neither substance is expected to meaningfully change the other. Both still carry their own individual risks. No interaction specific to Codeine and DOx is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.

Codeine
Weak, but metabolised unpredictably between people
Codeine also called
lean, purple drank, co-codamol, dihydrocodeine
DOx also called
dom, doc, doi, dob, don
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.