Mixing Codeine and Methamphetamine
- Codeine also called
- lean, purple drank, co-codamol, dihydrocodeine
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
Unsafe
A stimulant masking opioid sedation is how people miss the point at which they are overdosing. Methamphetamine's long duration means the opioid is often redosed several times across it, and the accumulated load becomes unopposed as the stimulant fades — typically while falling asleep.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Codeine and Methamphetamine?
Risk of serious physical or psychological harm. Not recommended under any circumstances.
This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.
- Codeine
- Weak, but metabolised unpredictably between people
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
- The Main Molecular Mechanisms Underlying Methamphetamine-Induced Neurotoxicity and Implications for Pharmacological Treatment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994595/
- Neurobiology and Clinical Manifestations of Methamphetamine Neurotoxicity. Psychiatric Times. https://www.psychiatrictimes.com/view/neurobiology-and-clinical-manifestations-methamphetamine-neurotoxicity
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.