Mixing GHB / GBL and Lithium
Caution
Together they add sedation, and dehydration can raise lithium levels; GHB's narrow dose range is the main danger. Take less GHB than usual, and do not use alone.
Additive sedation and impairment, plus dehydration risk affecting lithium levels. GHB's narrow dose window is the dominant danger here.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Headspace vs physical riskCan you mix GHB / GBL and Lithium?
MixSafe rates mixing GHB / GBL and Lithium as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: MixSafe research. Educational information, not medical advice.
- GHB / GBL also called
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
- Lithium also called
- lithium carbonate, lithobid, mood stabilizer
- Nayak SM et al., Johns Hopkins, 2021. https://pure.johnshopkins.edu/en/publications/classic-psychedelic-coadministration-with-lithium-but-not-lamotri/
- Ibuprofen interactions to avoid (renal lithium clearance). https://www.singlecare.com/blog/ibuprofen-interactions/
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.