Mixing GHB / GBL and SSRIs (antidepressants)
Low risk, no synergy
Neither substance is expected to meaningfully change the other. Both still carry their own individual risks.
Can you mix GHB / GBL and SSRIs (antidepressants)?
MixSafe rates mixing GHB / GBL and SSRIs as "Low risk, no synergy" — neither substance is expected to meaningfully change the other. Both still carry their own individual risks. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- GHB / GBL also called
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
- SSRIs also called
- ssri, zoloft, sertraline, lexapro, escitalopram, prozac
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.