Combination

Mixing Lithium and MXE

OtherDissociative
Lithium also called
lithium carbonate, lithobid, mood stabilizer
MXE also called
methoxetamine
Verdict

Dangerous

There is a risk of serotonin syndrome when combining Lithium with MXE, as Lithium can induce serotonin syndrome in conjunction with other serotonergic drugs, and MXE has shown a notable affinity for the serotonin transporter.

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix Lithium and MXE?

High risk of death or life-changing injury. Do not combine.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.