Mixing MAOIs and MXE
- MAOIs also called
- maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
- MXE also called
- methoxetamine
Unsafe
MAO-B inhibitors appear to increase the potency of MXE. MAO-A inhbitors have some negative reports associated with the combination but there isn't much information available
This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.
Can you mix MAOIs and MXE?
Risk of serious physical or psychological harm. Not recommended under any circumstances.
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.