Mixing MAOIs and NBOMes
Caution
MAOIs can make NBOMes much stronger and longer-lasting in ways that are hard to predict. Take less of each than usual, and do not use alone.
MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably
The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.
Headspace vs physical riskCan you mix MAOIs and NBOMes?
MixSafe rates mixing MAOIs and NBOMes as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- MAOIs also called
- maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
- NBOMes also called
- 25i, 25i-nbome, 25c-nbome, 25b-nbome, n-bomb, nbome
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Think this rating or note is wrong, or know a better source? Send it.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.