Combination

Mixing MAOIs and NBOMes

AntidepressantPsychedelic
MAOIs also called
maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
NBOMes also called
25i, 25i-nbome, 25c-nbome, 25b-nbome, n-bomb, nbome
Verdict

Caution

MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably

Risk / Headspace

The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.

Can you mix MAOIs and NBOMes?

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Related combinations

MAOIs withWhat not to mix with MAOIs →
NBOMes withWhat not to mix with NBOMes →
All combinations →

Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.