Combination

Mixing 5-MeO-xxT (5-MeO-DMT) and NBOMes

PsychedelicPsychedelic
Verdict

Caution

Both are unpredictable, NBOMes even on their own. This one is best avoided.

The 5-MeO class of tryptamines can be unpredictable in their interactions and the NBOMes are known to be unpredictable even alone. This combination is best avoided

Risk / Headspace

The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.

Headspace vs physical risk

Can you mix 5-MeO-xxT (5-MeO-DMT) and NBOMes?

MixSafe rates mixing 5-MeO-xxT and NBOMes as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

5-MeO-xxT also called
5-meo-dmt, 5-meo-mipt, 5-meo-dipt, foxy, toad, bufo
NBOMes also called
25i, 25i-nbome, 25c-nbome, 25b-nbome, n-bomb, nbome
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.