Caution

PCP can lower your opioid tolerance, making an overdose more likely.

Do this

Take less opioid than usual, do not use alone, and keep naloxone nearby.

General answer for Opioids: nothing specific to these two is documented.

Where the risk isTap for why
What “Caution” means

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

How the ratings work
The longer explanation

PCP can reduce opioid tolerance, increasing the risk of overdose

Sources (1)

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Other names
7-OH
7-hydroxymitragynine, 7-hydroxy mitragynine, 7-hydroxy, 7-oh tablets, 7oh tabs
Concentrated kratom alkaloid sold as tablets — without the leaf's ceiling on slowed breathing
PCP
phencyclidine, angel dust, angeldust, wet, sherm
Also searched as7-oh and angel dust, 7-oh and phencyclidine

Related combinations

All combinations →

Can you mix 7-OH and PCP (angel dust)?

MixSafe rates mixing 7-OH and PCP as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to 7-OH and PCP is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.