Mixing 7-OH and Ketamine (ket)

Q: How dangerous is 7-OH with Ketamine?

Dangerous: High risk of death or life-changing injury. Do not combine.

Q: Is it safe to mix 7-OH and ket?

MixSafe lists ket under Ketamine. That combination is rated "Dangerous". Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.

Dangerous

Together they can cause vomiting and unconsciousness.

Do this

Do not combine. Keep naloxone nearby, and put anyone who passes out on their side.

General answer for Opioids: nothing specific to these two is documented.

Where the risk isTap for why

In an emergency, call 911911 Never Use Alone Poison Control

What to do

Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
Give naloxone (Narcan) if you have it.It is sold over the counter in every US state and does no harm if opioids turn out not to be involved.
Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.

What “Dangerous” means

High risk of death or life-changing injury. Do not combine.

How the ratings work

The longer explanation

Both substances bring a risk of vomiting and unconsciousness. If the user falls unconscious while under the influence there is a severe risk of vomit aspiration if they are not placed in the recovery position.

Sources (1)

TripSit drug combination chart, retrieved 2026-08-20

Think this is wrong, or know a better source? Send it.

Other names

7-OH: 7-hydroxymitragynine, 7-hydroxy mitragynine, 7-hydroxy, 7-oh tablets, 7oh tabs; Concentrated kratom alkaloid sold as tablets — without the leaf's ceiling on slowed breathing
Ketamine: ket, special k, kitty, kittens, ketty, ketalar

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Related combinations

7-OH with

What not to mix with 7-OH →

Ketamine with

What not to mix with Ketamine →

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Can you mix 7-OH and Ketamine (ket)?

MixSafe rates mixing 7-OH and Ketamine as "Dangerous" — high risk of death or life-changing injury. Do not combine. No interaction specific to 7-OH and Ketamine is documented; this is the default for Opioids. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Opioids. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.