Mixing Ketamine (ket) and Xylazine (tranq)

Dangerous

Together this is how vets put animals under for surgery.

Do this

Do not combine. Put anyone who won't wake on their side and call for help; naloxone reverses neither.

Where the risk isTap for why
In an emergency, call 911911Never Use AlonePoison Control
What to do
  • Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
  • Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
  • Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
  • Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
  • Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Dangerous” means

High risk of death or life-changing injury. Do not combine.

How the ratings work
The longer explanation

Ketamine with xylazine is the standard injectable anaesthetic for animals, used to put them under for surgery. Outside a vet's monitoring that means deep unconsciousness, slowed breathing, and a heart rate and blood pressure that xylazine keeps pulling down. Naloxone reverses neither.

Sources (2)

Think this is wrong, or know a better source? Send it.

Other names
Ketamine
ket, special k, kitty, kittens, ketty, ketalar
Xylazine
tranq, tranq dope, zombie drug, anestesia de caballo, rompun, medetomidine
Animal sedative cut into fentanyl, as is its stronger cousin medetomidine — naloxone reverses neither
Also searched asket and tranq, special k and tranq, ket and tranq dope, special k and tranq dope
Add a third substance in the checker

Related combinations

Ketamine withWhat not to mix with Ketamine →
Xylazine withWhat not to mix with Xylazine →
All combinations →

Can you mix Ketamine (ket) and Xylazine (tranq)?

MixSafe rates mixing Ketamine and Xylazine as "Dangerous" — high risk of death or life-changing injury. Do not combine. Source: MixSafe research. Educational information, not medical advice.