Mixing Amphetamines (Adderall) and Methamphetamine (meth)
Caution
Nearly the same drug, but meth lasts far longer, so adding amphetamine stretches the strain on your heart for hours. Treat it as a redose, not a new drug.
Roughly the same molecule doing the same thing, so this is mostly a redose question wearing a combination's clothes. Methamphetamine is about twice as potent and lasts 8-24 hours against amphetamine's 4-6, so adding prescription stimulant to a meth session extends cardiovascular strain well past where either drug's effects are still worth having.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Headspace vs physical riskCan you mix Amphetamines (Adderall) and Methamphetamine (meth)?
MixSafe rates mixing Amphetamines and Methamphetamine as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: MixSafe research. Educational information, not medical advice.
- Amphetamines
- Prescription and street speed — Adderall, dexamphetamine
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
- Amphetamines also called
- adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
- The Main Molecular Mechanisms Underlying Methamphetamine-Induced Neurotoxicity and Implications for Pharmacological Treatment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994595/
- Neurobiology and Clinical Manifestations of Methamphetamine Neurotoxicity. Psychiatric Times. https://www.psychiatrictimes.com/view/neurobiology-and-clinical-manifestations-methamphetamine-neurotoxicity
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All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.