Combination

Mixing Caffeine and GHB / GBL

StimulantDepressant
Verdict

Low risk, no synergy

Neither substance is expected to meaningfully change the other. Both still carry their own individual risks.

Can you mix Caffeine and GHB / GBL?

MixSafe rates mixing Caffeine and GHB / GBL as "Low risk, no synergy" — neither substance is expected to meaningfully change the other. Both still carry their own individual risks. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

Caffeine also called
coffee, energy drink, espresso, pre-workout, red bull, monster
GHB / GBL also called
ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.