Mixing GHB / GBL and Methamphetamine (meth)
Caution
The stimulant hides how sedated you are; if it wears off first, the GHB can stop your breathing. Take less of each than usual, and do not use alone.
Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opiate may overcome the individual and cause respiratory arrest.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Headspace vs physical riskCan you mix GHB / GBL and Methamphetamine (meth)?
MixSafe rates mixing GHB / GBL and Methamphetamine as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to GHB / GBL and Methamphetamine is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
- GHB / GBL also called
- ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.