Combination

Mixing GHB / GBL and Opioids

DepressantOpioid
GHB / GBL also called
ghb, gbl, liquid ecstasy
Opioids also called
opiate, opiates, opioid, heroin, dope, smack
Verdict

Dangerous

The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position

Risk / Physical

The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.

Can you mix GHB / GBL and Opioids?

High risk of death or life-changing injury. Do not combine.

Opioids
Full agonists — heroin, oxycodone, morphine
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.