Combination

Mixing Ketamine and Lithium

DissociativeOther
Ketamine also called
ket, special k, kitty, kittens
Lithium also called
lithium carbonate, lithobid, mood stabilizer
Verdict

Low risk, no synergy

Lithium may enhance and prolong the antidepressant effects of ketamine.

Can you mix Ketamine and Lithium?

Neither substance is expected to meaningfully change the other. Both still carry their own individual risks.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Related combinations

Ketamine withWhat not to mix with Ketamine →
Lithium withWhat not to mix with Lithium →
All combinations →

Rated low / no synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.