Low risk, decreased effect

Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.

Do this

If one feels weaker than usual, wait it out instead of taking more.

Reported

Benzodiazepines take the edge off stimulant anxiety, which is why they are commonly used this way. The catch is that they blunt your sense of how much mephedrone is on board and cause blackouts, so redosing gets much easier to lose track of.

General answer for Benzodiazepines: nothing specific to these two is documented.

What “Low risk, decreased effect” means

Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.

How the ratings work
Sources (3)
Other names
Mephedrone
4-mmc, 4mmc, meow, m-cat, 4-methylmethcathinone, bath salts
Zolpidem
ambien, ambien cr, stilnox, edluar, intermezzo, zolpimist
Works like a benzo, plus sleepwalking and sleep-driving with no memory of it
Also searched asmeow and Ambien, m-cat and Ambien, meow and ambien cr, m-cat and ambien cr

Related combinations

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Can you mix Mephedrone (meow) and Zolpidem (Ambien)?

MixSafe rates mixing Mephedrone and Zolpidem as "Low risk, decreased effect" — low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous. No interaction specific to Mephedrone and Zolpidem is documented; this is the default for Benzodiazepines. Source: MixSafe research. Educational information, not medical advice.

This is a class-level answer, inherited from Benzodiazepines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.