Mixing Methylphenidate (Ritalin) and PCP (angel dust)
Unsafe
This combination easily tips into mania.
Avoid it.
General answer for Amphetamines: nothing specific to these two is documented.
What to do
- Say what was taken and how much.Responders need it, and in most US states Good Samaritan laws protect both of you from drug possession charges when you call for an overdose.
- Unresponsive: put them on their side, tilt the head back, and stay until help arrives.Never leave someone alone to “sleep it off”.
- Never Use Alone 1-800-484-3731Stays on the line and sends help if you stop responding.
- Full steps: what to do if it is already happeningOverdose signs, the recovery position, what to say on the call, and whether you can be charged for making it.
- Poison Control 1-800-222-1222Free and 24/7, for “is this bad?” before it becomes an emergency.
What “Unsafe” means
Risk of serious physical or psychological harm. Not recommended under any circumstances.
How the ratings workThe longer explanation
This combination can easily lead to hypermanic states
Sources (1)
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Other names
- Methylphenidate
- ritalin, ritalin la, concerta, focalin, dexmethylphenidate, methylin
- Not an amphetamine, but mixes much like one — most answers here are Adderall's
- PCP
- phencyclidine, angel dust, angeldust, wet, sherm
Related combinations
Can you mix Methylphenidate (Ritalin) and PCP (angel dust)?
MixSafe rates mixing Methylphenidate and PCP as "Unsafe" — risk of serious physical or psychological harm. Not recommended under any circumstances. No interaction specific to Methylphenidate and PCP is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.