Combination

Mixing 2C-x (2C-B) and Pregabalin (Lyrica)

PsychedelicDepressant
Verdict

Low risk, increased effect

Pregabalin may reduce the anxiety and other possible side effects of 2C-X drugs. Additionally, the combination may increase inhibition, dizziness, and risk of injury.

Can you mix 2C-x (2C-B) and Pregabalin (Lyrica)?

MixSafe rates mixing 2C-x and Pregabalin as "Low risk, increased effect" — low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

2C-x also called
2c-b, 2c-i, 2c-e, 2c-d, 2cb, 2ci
Pregabalin also called
lyrica, pregablin, gabapentin, gaba, neurontin, gabbies
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.