Mixing Alcohol and Ibuprofen (Advil)
Caution
Both are hard on the stomach and kidneys, raising the risk of bleeding and kidney injury. Avoid regular use together, and do not take ibuprofen when dehydrated.
Both irritate the stomach lining and both stress the kidneys. Together they raise the risk of gastrointestinal bleeding and ulcers, and of acute kidney injury when dehydrated. Occasional use is usually tolerated; regular or heavy drinking with regular NSAID use is a well-documented bleeding risk.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Headspace vs physical riskCan you mix Alcohol and Ibuprofen (Advil)?
MixSafe rates mixing Alcohol and Ibuprofen as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. Source: MixSafe research. Educational information, not medical advice.
- Alcohol also called
- alc, booze, beer, wine, liquor, ethanol
- Ibuprofen also called
- advil, motrin, nurofen, nsaid, nsaids, naproxen
- Ibuprofen and Alcohol: Is it Safe to Mix NSAIDs and Alcohol? https://alcohol.org/mixing-with/nonsteroidal-anti-inflammatory/
- Mixing NSAIDs with alcohol. GoodRx. https://www.goodrx.com/classes/nsaids/mixing-with-alcohol
- Ibuprofen interactions to avoid. SingleCare. https://www.singlecare.com/blog/ibuprofen-interactions/
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Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.