Combination
Mixing Amphetamines and Benzodiazepines
StimulantDepressant
- Amphetamines also called
- adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
- Benzodiazepines also called
- benzodiazepine, benzos, benzo, xanax, alprazolam, valium
Verdict
Low risk, decreased effect
Both can dull each other's effects, so if one wears off before the other it's possible to overdose due to the lack of counteraction
Can you mix Amphetamines and Benzodiazepines?
Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.
- Amphetamines
- Prescription and street speed — Adderall, dexamphetamine
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Benzodiazepines withWhat not to mix with Benzodiazepines →
Rated low / decrease. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.