Mixing Amphetamines (Adderall) and Benzodiazepines (Xanax)
Low risk, decreased effect
Both can dull each other's effects, so if one wears off before the other it's possible to overdose due to the lack of counteraction
Can you mix Amphetamines (Adderall) and Benzodiazepines (Xanax)?
MixSafe rates mixing Amphetamines and Benzodiazepines as "Low risk, decreased effect" — low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.
- Amphetamines
- Prescription and street speed — Adderall, dexamphetamine
- Amphetamines also called
- adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
- Benzodiazepines also called
- benzodiazepine, benzos, benzo, xanax, alprazolam, valium
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
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Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Rated low / decrease. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.