Caution

The stimulant hides how sedated you are; if it wears off first, the GHB can stop your breathing.

Do this

Take less of each than usual, and do not use alone.

General answer for Amphetamines: nothing specific to these two is documented.

Where the risk isTap for why
What “Caution” means

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

How the ratings work
The longer explanation

Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opiate may overcome the individual and cause respiratory arrest.

Sources (1)

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Other names
GHB / GBL
ghb, gbl, liquid ecstasy, 1,4-butanediol, bdo, 1,4-bd
Methylphenidate
ritalin, ritalin la, concerta, focalin, dexmethylphenidate, methylin
Not an amphetamine, but mixes much like one — most answers here are Adderall's
Also searched asliquid G and Ritalin, ghb and Ritalin, liquid G and ritalin la, ghb and ritalin la

Related combinations

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Can you mix GHB / GBL (liquid G) and Methylphenidate (Ritalin)?

MixSafe rates mixing GHB / GBL and Methylphenidate as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to GHB / GBL and Methylphenidate is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.