Combination

Mixing DMT and Pregabalin

PsychedelicDepressant
DMT also called
n,n-dmt, dimethyltryptamine, changa
Pregabalin also called
lyrica, pregablin, gabapentin, gaba
Verdict

Low risk, increased effect

Pregabalin may reduce the anxiety and other possible side effects of DMT. Additionally, the combination may increase inhibition, dizziness, and risk of injury.

Can you mix DMT and Pregabalin?

Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Related combinations

DMT withWhat not to mix with DMT →
Pregabalin withWhat not to mix with Pregabalin →
All combinations →

Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.