Combination

Mixing GHB / GBL and Nitrous Oxide

DepressantDissociative
GHB / GBL also called
ghb, gbl, liquid ecstasy
Nitrous Oxide also called
nitrous, n2o, nos, laughing gas, whippits, whippets
Verdict

Caution

Both substances potentiate the ataxia and sedation caused by the other and can lead to unexpected loss of consciousness at high doses. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Memory blackouts are likely.

Risk / Headspace

The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.

Can you mix GHB / GBL and Nitrous Oxide?

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

Open this in the checker

Related combinations

All combinations →

Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.