Mixing Ketamine (ket) and Methylphenidate (Ritalin)

Caution

Likely to raise blood pressure, and moving around on high doses of both risks injury.

Do this

Keep doses sensible, and avoid moving around much on high doses.

General answer for Amphetamines: nothing specific to these two is documented.

Where the risk isTap for why
What “Caution” means

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

How the ratings work
The longer explanation

No unexpected interactions, though likely to increase blood pressure but not an issue with sensible doses. Moving around on high doses of this combination may be ill advised due to risk of physical injury.

Sources (1)

Think this is wrong, or know a better source? Send it.

Other names
Ketamine
ket, special k, kitty, kittens, ketty, ketalar
Methylphenidate
ritalin, ritalin la, concerta, focalin, dexmethylphenidate, methylin
Not an amphetamine, but mixes much like one — most answers here are Adderall's
Also searched asket and Ritalin, special k and Ritalin, ket and ritalin la, special k and ritalin la
Add a third substance in the checker

Related combinations

Ketamine withWhat not to mix with Ketamine →
Methylphenidate withWhat not to mix with Methylphenidate →
All combinations →

Can you mix Ketamine (ket) and Methylphenidate (Ritalin)?

MixSafe rates mixing Ketamine and Methylphenidate as "Caution" — carries risk that is worth understanding before combining. Reduce doses and do not use alone. No interaction specific to Ketamine and Methylphenidate is documented; this is the default for Amphetamines. Source: TripSit drug combination chart, retrieved 2026-08-20. Educational information, not medical advice.

This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.