Mixing MDMA and Pregabalin
- MDMA also called
- molly, ecstasy, ecstacy, xtc, mandy, pills
- Pregabalin also called
- lyrica, pregablin, gabapentin, gaba
Unsafe
There is a significant risk of seizures from this combination. Amphetamines increase respiration rate allowing for a higher dose of sedatives than normal. If amphetamines wears off first, recreational dosages of pregabalin may overcome the individual and cause respiratory arrest. Both substances at recreational dosages cause strain of the heart and may lead to further dangerous heart complications. Medical dosages are not reported to be a concern
This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.
Can you mix MDMA and Pregabalin?
Risk of serious physical or psychological harm. Not recommended under any circumstances.
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.