Combination

Mixing Mephedrone and Pregabalin

StimulantDepressant
Mephedrone also called
4-mmc, 4mmc, meow, m-cat, 4-methylmethcathinone, bath salts
Pregabalin also called
lyrica, pregablin, gabapentin, gaba
Verdict

Unsafe

There is a significant risk of seizures from this combination. Mephedrone increases respiration rate allowing for a higher dose of sedatives than normal. If mephedrone wears off first, recreational dosages of pregabalin may overcome the individual and cause respiratory arrest. Both substances at recreational dosages cause strain of the heart and may lead to further dangerous heart complications.

Risk / Physical

The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.

Can you mix Mephedrone and Pregabalin?

Risk of serious physical or psychological harm. Not recommended under any circumstances.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.